Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody
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Description
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells ; ;.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7Z3Z4 |
| Gene ID | 143689 |
| OMIM | 610315 |
| Background | Antibody anti-PIWIL4 |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
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Human PIWIL4 (Piwi-Like protein 4 ) ELISA Kit
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Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody
PIWIL4 Antibody is a Rabbit Polyclonal antibody against PIWIL4. PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Associates with secondary piRNAs antisense and PIWIL2/MILI is required for such association.
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Piwi Like RNA-Mediated Gene Silencing 4 (PIWIL4) Antibody
PIWIL4 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells ; ;.
Ver Producto