Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody

Este producto es parte de SERPINF1 - serpin family F member 1
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299€ (100 µl)

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935106861
info@markelab.com
name
Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx131580
tested applications
IHC

Description

Pigment Epithelium-Derived Factor Antibody is a Rabbit Polyclonal against Pigment Epithelium-Derived Factor.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Pigment Epithelium-Derived Factor / PEDF (SERPINF1)
Immunogen: abx650847 - Recombinant PEDF (Gln20-Thr418) expressed in E. coli
Host
Rabbit
Reactivity
Rat
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
WB (Predicted): 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
IHC
Buffer
PBS, pH 7.4, containing 0.02% Sodium azide, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q80ZA3
Gene ID
287526
Alias
OI6,OI12,PEDF,EPC-1,PIG35,Pigment epithelium-derived factor,Cell proliferation-inducing gene 35 protein,Serpin F1
Background
Antibody anti-SERPINF1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

SERPINF1, also known as pigment epithelium-derived factor (PEDF), is a member of the serpin (serine protease inhibitor) family, though it has unique properties distinct from classical serpins. Unlike most serpins, SERPINF1 does not function as a typical protease inhibitor but is instead a multifunctional protein with potent anti-angiogenic, neuroprotective, and anti-inflammatory effects. First identified in the pigment epithelium of the eye, it has since been found in a variety of tissues and is now recognized as a crucial player in many biological processes, including the inhibition of abnormal blood vessel growth and tissue protection. SERPINF1 is highly expressed in the eye, particularly in the retinal pigment epithelium (RPE) and other neural tissues. It is most famous for its role in ocular health, but its functions extend to other organs, such as the liver, heart, skin, and brain.

Related Products

abx650847

Rat Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Protein

Rat PEDF Protein is a recombinant Rat protein expressed in E. coli.

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