Rat Pigment Epithelium-Derived Factor / PEDF (SERPINF1) Protein
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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein SERPINF1
proveedor
Abbexareference
abx650847Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat PEDF Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
SERPINF1, also known as pigment epithelium-derived factor (PEDF), is a member of the serpin (serine protease inhibitor) family, though it has unique properties distinct from classical serpins. Unlike most serpins, SERPINF1 does not function as a typical protease inhibitor but is instead a multifunctional protein with potent anti-angiogenic, neuroprotective, and anti-inflammatory effects. First identified in the pigment epithelium of the eye, it has since been found in a variety of tissues and is now recognized as a crucial player in many biological processes, including the inhibition of abnormal blood vessel growth and tissue protection. SERPINF1 is highly expressed in the eye, particularly in the retinal pigment epithelium (RPE) and other neural tissues. It is most famous for its role in ocular health, but its functions extend to other organs, such as the liver, heart, skin, and brain.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Pigment Epithelium-Derived Factor / PEDF (SERPINF1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 58.2 kDa Observed MW (SDS-PAGE): 58.2 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gln20-Thr418 Tag: N-terminal His tag and SUMO tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
SERPINF1
dry ice
No
availability
Shipped within 5-7 working days.
alias
OI6,OI12,PEDF,EPC-1,PIG35,Pigment epithelium-derived factor,Cell proliferation-inducing gene 35 protein,Serpin F1
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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