Pig Vascular Endothelial Growth Factor A (VEGFA) Protein

Este producto es parte de VEGFA - Vascular Endothelial Growth Factor A
Pig Vascular Endothelial Growth Factor A (VEGFA) Protein

Pida mas información

935106861

info@markelab.com

Precio

442€ (50 µg)

Protein VEGFA

proveedor

Abbexa

reference

abx069633

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Vascular Endothelial Growth Factor A (VEGFA) is a recombinant Pig protein produced in a Prokaryotic expression system (E. coli).

Background

VEGFA is a key member of the vascular endothelial growth factor (VEGF) family and plays a crucial role in angiogenesis, vascular permeability, and endothelial cell proliferation VEGFA binds primarily to its receptors VEGFR-1 and VEGFR-2, triggering signaling pathways like PI3K/AKT and ERK/MAPK to promote blood vessel formation during embryonic development, wound healing, and tissue repair Dysregulated VEGFA expression is associated with pathological angiogenesis observed in cancer, diabetic retinopathy, and age-related macular degeneration (AMD) VEGFA also increases vascular permeability by altering endothelial junctions, contributing to fluid leakage in conditions such as inflammation and tumors Targeted therapies, such as bevacizumab and other anti-VEGF agents, inhibit VEGFA activity to suppress angiogenesis and tumor growth in various cancers and ocular diseases

Características del producto

category

Proteins and Peptides

origin

Pig

host

E. coli

immunogen target

Vascular Endothelial Growth Factor A (VEGFA)

host

E. coli

conjugation

Unconjugated

form

Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.4 mg/ml. Do not vortex.

tested applications

WB, SDS-PAGE

size 1

50 µg

size 2

100 µg

size 3

200 µg

size 4

500 µg

size 5

1 mg

observerd MW

Molecular Weight: Calculated MW: 49.2 kDa Observed MW (SDS-PAGE): 49 kDa Concentration: Prior to lyophilization: 50 µg/ml Sequence Fragment: Ala27-Arg190 Tag: N-terminal His tag and GST tag

purity

> 97%

buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

VEGFA

dry ice

No

availability

Shipped within 5-12 working days.

alias

L-VEGF,MVCD1,VEGF,VPF,Vascular permeability factor

uniprot id

https://www.uniprot.org/uniprotkb/P49151

note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

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