Pig Muscarinic Acetylcholine Receptor M1 (CHRM1) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Pig Muscarinic Acetylcholine Receptor M1 (CHRM1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx361184
Tested Applications
ELISA
Description
Pig Muscarinic Acetylcholine Receptor M1 (CHRM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Pig M-AChR concentrations in serum, plasma and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Muscarinic Acetylcholine Receptor M1 (CHRM1) |
| Reactivity | Pig |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | CHRM1,M1 muscarinic acetylcholine receptor,Chrm-1,M1R,cholinergic receptor muscarinic 1,cholinergic receptor,cholinergic receptor, muscarinic 1, M1 receptor,M1, HM1 |
| Background | Elisa Kits for: CHRM1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
CHRM1 encodes the cholinergic receptor muscarinic 1, which is a member of the muscarinic acetylcholine receptor family. These receptors are G protein-coupled receptors (GPCRs) that mediate the actions of acetylcholine, a key neurotransmitter in the central nervous system (CNS) and peripheral tissues. CHRM1 is primarily expressed in the cerebral cortex, hippocampus, and basal ganglia, playing an essential role in cognitive processes such as learning, memory, and attention. Activation of CHRM1 leads to the stimulation of phospholipase C (PLC) via Gq/11 proteins, which increases intracellular calcium ion concentration and activates protein kinase C (PKC). Dysregulation of CHRM1 has been associated with neurological and psychiatric disorders, including Alzheimer's disease, schizophrenia, and epilepsy. Pharmacologically, CHRM1 agonists enhance cognitive function, while antagonists can alleviate conditions like muscle spasms and excessive salivation. CHRM1 remains a critical target in neurodegenerative research, as modulation of this receptor may restore acetylcholine signaling and improve cognitive decline.
Productos relacionados
Muscarinic Acetylcholine Receptor M1 (CHRM1) Antibody
CHRM1 Antibody is a Rabbit Polyclonal antibody against CHRM1. The muscarinic cholinergic receptors belong to a larger fa…
Ver producto
Muscarinic Acetylcholine Receptor M1 (CHRM1) Antibody
Rabbit polyclonal antibody against CHRM1 protein. Immunogen region is Internal.…
Ver producto
Rat Cholinergic Receptor, Muscarinic 1 (CHRM1) Protein
Rat Cholinergic Receptor, Muscarinic 1 (CHRM1) is a recombinant Rat protein expressed in E. coli.…
Ver producto