Pig Interleukin 13 (IL13) Protein

Este producto es parte de IL13 - interleukin 13
Pig Interleukin 13 (IL13) Protein

Pida mas información

935106861

info@markelab.com

Precio

338€ (5 µg)

Protein IL13

proveedor

Abbexa

reference

abx670318

Tested Applications

ELISA, WB

reactivity

status

RUO

clonality

Descripción

Pig Interleukin 13 (IL13) Protein is a Recombinant protein expressed in Pichia pastoris. This product can be used in a sandwich ELISA assay with


Background

Interleukin 13 (IL13) is a cytokine primarily involved in the regulation of immune responses, particularly those associated with allergies, asthma, and parasitic infections. IL-13 is produced mainly by T-helper type 2 (Th2) cells, a subset of CD4+ T cells that are central to immune responses against extracellular pathogens, especially helminths, and in promoting allergic reactions. Other cell types, including natural killer (NK) cells, mast cells, basophils, eosinophils, and innate lymphoid cells (ILC2), also secrete IL-13. IL-13 plays a critical role in coordinating allergic inflammation by promoting the production of IgE by B cells, mucus secretion in the lungs, and tissue remodeling, all of which are hallmarks of allergic diseases such as asthma. Importantly, IL-13 shares some overlapping functions with IL-4, another Th2 cytokine, due to the fact that both cytokines signal through a shared receptor subunit, the IL-4 receptor alpha (IL-4Rα). Despite this overlap, IL-13 also exerts unique effects, particularly in tissue fibrosis and remodeling, where it is a key driver.

Características del producto

category

Proteins and Peptides


origin

Pig


host

Yeast


immunogen target

Interleukin 13 (IL13)


host

Yeast


conjugation

Unconjugated


form

Lyophilized Reconstitute in 20 µl sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommended to gently mix the vial after reconstitution.


tested applications

ELISA, WB


size 1

5 µg


observerd MW

Molecular Weight: 13.2 kDa Sequence Fragment: 11-131 AA.


purity

> 95% (SDS-PAGE)


recommended dilution

Optimal dilutions/concentrations should be determined by the end user.


buffer

Prior to lyophilization: Phosphate buffered saline, 10% Trehalose.


storage

Store at 4 °C for up to one week. For long-term storage, store at -20 °C. Avoid repeated freeze/thaw cycles.


or code

IL13


dry ice

No


availability

Shipped within 3-7 working days.


alias

P600,IL-13,NC30


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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