Pig Interleukin 13 (IL13) Protein

Este producto es parte de IL13 - interleukin 13
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338€ (5 µg)

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935106861
info@markelab.com
name
Pig Interleukin 13 (IL13) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx670318
tested applications
ELISA, WB

Description

Pig Interleukin 13 (IL13) Protein is a Recombinant protein expressed in Pichia pastoris. This product can be used in a sandwich ELISA assay with

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interleukin 13 (IL13)
Host
Yeast
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Origin
Pig
Conjugation
Unconjugated
Observed MW
Molecular Weight: 13.2 kDa
Sequence Fragment: 11-131 AA.
Purity
> 95% (SDS-PAGE)
Size 1
5 µg
Form
Lyophilized Reconstitute in 20 µl sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommended to gently mix the vial after reconstitution.
Tested Applications
ELISA, WB
Buffer
Prior to lyophilization: Phosphate buffered saline, 10% Trehalose.
Availability
Shipped within 3-7 working days.
Storage
Store at 4 °C for up to one week. For long-term storage, store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q95J68
Alias
P600,IL-13,NC30
Background
Protein IL13
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin 13 (IL13) is a cytokine primarily involved in the regulation of immune responses, particularly those associated with allergies, asthma, and parasitic infections. IL-13 is produced mainly by T-helper type 2 (Th2) cells, a subset of CD4+ T cells that are central to immune responses against extracellular pathogens, especially helminths, and in promoting allergic reactions. Other cell types, including natural killer (NK) cells, mast cells, basophils, eosinophils, and innate lymphoid cells (ILC2), also secrete IL-13. IL-13 plays a critical role in coordinating allergic inflammation by promoting the production of IgE by B cells, mucus secretion in the lungs, and tissue remodeling, all of which are hallmarks of allergic diseases such as asthma. Importantly, IL-13 shares some overlapping functions with IL-4, another Th2 cytokine, due to the fact that both cytokines signal through a shared receptor subunit, the IL-4 receptor alpha (IL-4Rα). Despite this overlap, IL-13 also exerts unique effects, particularly in tissue fibrosis and remodeling, where it is a key driver.

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