Pig Interleukin 13 (IL13) Protein
351€ (5 µg)
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Name
Pig Interleukin 13 (IL13) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx670318
Tested Applications
ELISA, WB
Description
Pig Interleukin 13 (IL13) Protein is a Recombinant protein expressed in Pichia pastoris. This product can be used in a sandwich ELISA assay with
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Interleukin 13 (IL13) |
| Host | Yeast |
| Assay Type | Sequence Fragment: 11-131 AA. |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Pig |
| Conjugation | Unconjugated |
| Observed MW | 13.2 kDa |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 5 µg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: Phosphate buffered saline, 10% Trehalose. |
| Availability | Shipped within 3-7 working days. |
| Storage | Store at 4°C for up to one week. For long-term storage, store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q95J68 |
| Alias | P600,IL-13,NC30 |
| Background | Protein IL13 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in 20 µl sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommended to gently mix the vial after reconstitution. |
Background
Interleukin 13 (IL13) is a cytokine primarily involved in the regulation of immune responses, particularly those associated with allergies, asthma, and parasitic infections. IL-13 is produced mainly by T-helper type 2 (Th2) cells, a subset of CD4+ T cells that are central to immune responses against extracellular pathogens, especially helminths, and in promoting allergic reactions. Other cell types, including natural killer (NK) cells, mast cells, basophils, eosinophils, and innate lymphoid cells (ILC2), also secrete IL-13. IL-13 plays a critical role in coordinating allergic inflammation by promoting the production of IgE by B cells, mucus secretion in the lungs, and tissue remodeling, all of which are hallmarks of allergic diseases such as asthma. Importantly, IL-13 shares some overlapping functions with IL-4, another Th2 cytokine, due to the fact that both cytokines signal through a shared receptor subunit, the IL-4 receptor alpha (IL-4Rα). Despite this overlap, IL-13 also exerts unique effects, particularly in tissue fibrosis and remodeling, where it is a key driver.
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