Bovine IL13(Interleukin-13) ELISA Kit

Este producto es parte de IL13 - interleukin 13
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935106861
info@markelab.com
name
Bovine IL13(Interleukin-13) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EB0171

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
bovine
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich ELISA, Double Antibody
Test Range
15.625-1000pg/ml
Size 1
96T
Sample Type
Serum,Plasma,Tissue homogenates,Other biological fluids
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 6 months
UniProt ID
Q9XSV9
Alias
P600,IL-13,NC30
Background
Elisa Kits IL13
Status
RUO

Interleukin 13 (IL13) is a cytokine primarily involved in the regulation of immune responses, particularly those associated with allergies, asthma, and parasitic infections. IL-13 is produced mainly by T-helper type 2 (Th2) cells, a subset of CD4+ T cells that are central to immune responses against extracellular pathogens, especially helminths, and in promoting allergic reactions. Other cell types, including natural killer (NK) cells, mast cells, basophils, eosinophils, and innate lymphoid cells (ILC2), also secrete IL-13. IL-13 plays a critical role in coordinating allergic inflammation by promoting the production of IgE by B cells, mucus secretion in the lungs, and tissue remodeling, all of which are hallmarks of allergic diseases such as asthma. Importantly, IL-13 shares some overlapping functions with IL-4, another Th2 cytokine, due to the fact that both cytokines signal through a shared receptor subunit, the IL-4 receptor alpha (IL-4Rα). Despite this overlap, IL-13 also exerts unique effects, particularly in tissue fibrosis and remodeling, where it is a key driver.

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