Pig Intercellular Adhesion Molecule 1 (ICAM1) Protein

Este producto es parte de ICAM1 - Intercellular adhesion molecule 1
Pig Intercellular Adhesion Molecule 1 (ICAM1) Protein

Pida mas información

935106861

info@markelab.com

Precio

455€ (50 µg)

Protein ICAM1

proveedor

Abbexa

reference

abx168646

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Pig ICAM1 Protein is a recombinant Pig protein produced in a Prokaryotic expression system (E. coli).


Background

Intercellular Adhesion Molecule 1 (ICAM-1) is a protein encoded by the ICAM1 gene in humans. It plays a crucial role in the immune response by aiding in the adhesion of leukocytes to the endothelial cells lining blood vessels. ICAM-1. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into respiratory epithelium. ICAM-1 is a transmembrane protein possessing an amino-terminus extracellular domain, a single transmembrane domain, and a carboxy-terminus cytoplasmic domain. The structure of ICAM-1 is characterized by heavy glycosylation, and the protein’s extracellular domain is composed of multiple loops created by disulfide bridges within the protein. ICAM-1 is important for the process of leukocyte extravasation, which is how white blood cells move from the bloodstream to infected or injured tissues. It helps leukocytes stick to endothelial cells, a crucial step in the inflammatory response. ICAM-1 can also trigger intracellular signaling events when it binds to its ligands, influencing cellular processes related to inflammation and immune responses.

Características del producto

category

Proteins and Peptides


origin

Pig


host

E. coli


immunogen target

Intercellular Adhesion Molecule 1 (ICAM1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

50 µg


size 2

100 µg


size 3

200 µg


size 4

500 µg


size 5

1 mg


observerd MW

Molecular Weight: Calculated MW: 24.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Gly27-Ala209 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ICAM1


dry ice

No


availability

Shipped within 5-7 working days.


alias

BB2,CD54,P3.58,ICAM-1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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