Pig Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Protein

Este producto es parte de IGFBP7 - Insulin Like Growth Factor Binding Protein 7
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2197€ (1 mg)

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935106861
info@markelab.com
name
Pig Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx653874
tested applications
WB, SDS-PAGE

Description

Pig Insulin Like Growth Factor Binding Protein 7 (IGFBP7) Protein is a Recombinant Pig protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Insulin Like Growth Factor Binding Protein 7 (IGFBP7)
Host
E. coli
Origin
Pig
Conjugation
Unconjugated
Observed MW
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Please enquire.
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
1 mg
Size 2
5 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 1-2 months.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
AGM,PSF,TAF,FSTL2,IBP-7,MAC25,IGFBP-7,RAMSVPS,IGFBP-7v,IGFBPRP1,IGF-binding protein 7
Background
Protein IGFBP7
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

IGFBP7 is a member of the insulin-like growth factor binding protein family that regulates the availability and activity of insulin-like growth factors (IGFs) by binding to them with high affinity Unlike other IGFBPs, IGFBP7 also binds to insulin, modulating its signaling and promoting metabolic homeostasis IGFBP7 plays a critical role in regulating cell growth, apoptosis, and senescence and has anti-tumorigenic properties by inhibiting the mitogenic effects of IGFs Its expression is downregulated in cancers such as colorectal, breast, and prostate cancer where it acts as a tumor suppressor IGFBP7 also plays roles in cardiovascular health by influencing vascular smooth muscle cell proliferation and in fibrosis by mediating tissue remodeling and extracellular matrix deposition

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