Pig Hepatocyte Growth Factor (HGF) Protein
234€ (2 µg)
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935106861
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name
Pig Hepatocyte Growth Factor (HGF) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx261778
tested applications
SDS-PAGE
Description
Pig Hepatocyte Growth Factor (HGF) is a native Pig cytokine isolated from Pig Liver.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Hepatocyte Growth Factor (HGF) |
| Host | Pig |
| Origin | Pig |
| Conjugation | Unconjugated |
| Expression | Native |
| Purity | > 98% (SDS-PAGE and RP-HPLC) |
| Purification | Purified by proprietary chromatographic techniques. |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Lyophilized Reconstitute in sterile 18 MΩ · cm water to a concentration of at least 100 µg/ml. This stock solution can be further diluted if required. |
| Tested Applications | SDS-PAGE |
| Buffer | Does not contain preservatives. |
| Availability | Shipped within 5-10 working days. |
| Storage | The lyophilized form is stable at room temperature for up to 3 weeks. It is recommended to store this product lyophilized and desiccated at -18 °C or lower. After reconstitution, store at 4 °C for up to 7 days, or at -18 °C or lower for long-term storage. For long-term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | SF,HGFB,HPTA,F-TCF,DFNB39,Fibroblast-Derived Tumor Cytotoxic Factor |
| Background | Protein HGF |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Hepatocyte Growth Factor (HGF), also known as scatter factor, is a multifunctional cytokine primarily secreted by mesenchymal cells. It plays a pivotal role in various physiological and pathological processes, including cell proliferation, migration, morphogenesis, and angiogenesis. HGF exerts its biological effects through binding to its receptor, c-MET, a tyrosine kinase receptor highly expressed on epithelial cells, endothelial cells, and other cell types. This ligand-receptor interaction activates numerous signaling pathways, such as PI3K/AKT and MAPK, promoting tissue regeneration and wound healing. HGF is critically involved in liver regeneration and repair mechanisms, hence its name, but it also has significant implications in tumor progression and metastasis in cancers where c-MET is overexpressed or dysregulated. Clinically, HGF and its receptor c-MET are being explored as therapeutic targets for cancer treatments, given their role in oncogenesis and tumor angiogenesis. Elevated HGF levels in plasma have also been investigated as potential biomarkers for various diseases, including liver dysfunction and cancers.
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