Pig CD59 Glycoprotein (CD59) ELISA Kit

Este producto es parte de CD59 - CD59 molecule
Pig CD59 Glycoprotein (CD59) ELISA Kit
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Pig CD59 Glycoprotein (CD59) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx361750
Tested Applications
ELISA

Description

Pig CD59 Glycoprotein (CD59) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Pig CD59 Glycoprotein (CD59) concentrations in serum, plasma and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
CD59 Glycoprotein (CD59)
Reactivity
Pig
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
31.2 pg/ml - 2000 pg/ml
Sensitivity
18.8 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
CD59 blood group,1F5,EJ16,EJ30,EL32,G344,MIN1,MIN2,MIN3,MIRL,HRF20,MEM43,MIC11,MSK21,16.3A5,HRF-20,MAC-IP,CD59 glycoprotein,MAC-inhibitory protein,MAC-IP,Membrane attack complex inhibition factor,MACIF
Background
Elisa Kits for: CD59
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

CD59 molecule (CD59) is a small, glycosylphosphatidylinositol (GPI)-anchored protein expressed on the surface of a wide variety of human cells. Its primary function is to inhibit the formation of the membrane attack complex (MAC) during the complement cascade, which is part of the immune system’s defense mechanism. By binding to components C8 and C9 of the complement system, CD59 prevents the insertion and polymerization of MAC into cell membranes, protecting host cells from lysis. This protective role is critical in maintaining cellular integrity and preventing autoimmune damage. CD59 also exhibits roles beyond complement regulation; it has been implicated in modulating T-cell activation and participating in signal transduction pathways through its interactions with other membrane proteins. Deficiency or dysfunction of CD59 is associated with certain pathological conditions, such as paroxysmal nocturnal hemoglobinuria (PNH), where red blood cells become highly susceptible to complement-mediated lysis. Additionally, CD59 is being studied for its potential role in cancer, as its overexpression in tumor cells may help them evade immune surveillance. Its broad cellular expression and functional versatility make CD59 a crucial regulator of immune and cellular processes.

Productos relacionados

abx001417

CD59 Glycoprotein (CD59) Antibody

CD59 Antibody is a Rabbit Polyclonal antibody against CD59. This gene encodes a cell surface glycoprotein that regulates…

Ver producto
abx011952

CD59 Glycoprotein (CD59) Antibody

This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymph…

Ver producto
abx021467

CD59 Glycoprotein (CD59) Antibody

CD59 Antibody is a Mouse monoclonal antibody for human cds against CD59.…

Ver producto