Pig Angiogenin (ANG) Protein
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Description
Recombinant Angiogenin (ANG) is a recombinant Pig protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Angiogenin (ANG) |
| Host | E. coli |
| Origin | Pig |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 15.5 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Lys1-Gln123 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 1 mg |
| Size 2 | 5 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 1-2 months. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P31346 |
| Alias | ANG,RNASE5,Ribonuclease 5 |
| Background | Protein ANG |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Angiogenin (ANG) is a protein that plays a significant role in angiogenesis. It is a member of the ribonuclease superfamily, but unlike other members that primarily function in RNA degradation, angiogenin has distinct functions related to blood vessel formation and tissue repair. The primary role of angiogenin is to promote the growth of new blood vessels from existing ones. This is crucial in processes like wound healing, embryonic development, and tissue regeneration. Angiogenin has ribonuclease activity, meaning it can cleave RNA molecules. However, its angiogenic activity is independent of this enzymatic function. Angiogenin acts on endothelial cells, which line the inside of blood vessels. It stimulates these cells to proliferate, migrate, and form new blood vessels. It also promotes cell survival and protects cells from apoptosis (programmed cell death), which is important for the stability of newly formed blood vessels.
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