Rat Angiogenin (ANG) Protein

Este producto es parte de ANG - Angiogenin
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234€ (10 µg)

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935106861
info@markelab.com
name
Rat Angiogenin (ANG) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065309
tested applications
WB, SDS-PAGE

Description

Rat Angiogenin (ANG) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Angiogenin (ANG)
Host
E. coli
Origin
Rat
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 17.0 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Gln25-Phe142

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q5WRG2
Alias
ANG,RNASE5,Ribonuclease 5
Background
Protein ANG
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Angiogenin (ANG) is a protein that plays a significant role in angiogenesis. It is a member of the ribonuclease superfamily, but unlike other members that primarily function in RNA degradation, angiogenin has distinct functions related to blood vessel formation and tissue repair. The primary role of angiogenin is to promote the growth of new blood vessels from existing ones. This is crucial in processes like wound healing, embryonic development, and tissue regeneration. Angiogenin has ribonuclease activity, meaning it can cleave RNA molecules. However, its angiogenic activity is independent of this enzymatic function. Angiogenin acts on endothelial cells, which line the inside of blood vessels. It stimulates these cells to proliferate, migrate, and form new blood vessels. It also promotes cell survival and protects cells from apoptosis (programmed cell death), which is important for the stability of newly formed blood vessels.

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