Pig Adenosine Deaminase 2 (ADA2) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ADA2
proveedor
Abbexareference
abx514725Tested Applications
ELISAreactivity
Pigstatus
RUOclonality
Descripción
Pig Adenosine Deaminase 2 (ADA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Pig Adenosine Deaminase 2 (ADA2) concentrations in serum, plasma, cell culture supernatants and other biological fluids.
Background
ADA2, encoded by the CECR1 gene, is a secreted protein that belongs to the adenosine deaminase family but has a distinct role compared to ADA. While ADA mainly regulates purine metabolism, ADA2 functions as a growth factor and modulates immune and vascular systems. It plays a significant role in macrophage activation, promoting M2 polarization, and regulating endothelial cell proliferation and angiogenesis. ADA2 is highly expressed in immune-related tissues, particularly monocytes and macrophages. Loss-of-function mutations in ADA2 cause Deficiency of ADA2 (DADA2), an autoinflammatory disorder characterized by systemic vasculitis, early-onset stroke, immunodeficiency, and bone marrow failure. Elevated ADA2 activity has also been linked to tumor progression and inflammation. ADA2 is a critical biomarker and therapeutic target for managing vasculitic and immune-related diseases.
Características del producto
category
ELISA Kits
immunogen target
Adenosine Deaminase 2 (ADA2)
reactivity
Pig
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.15 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, cell culture supernatants and other biological fluids.
size 1
96 tests
alias
ADGF,CECR1,IDGFL
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ADA2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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