Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3) Antibody

Este producto es parte de NR2E - nuclear receptor subfamily 2 group E member
Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3) Antibody
351€ (100 µg)

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Name
Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx375943
Tested Applications
ELISA, WB

Description

Nuclear Receptor Subfamily 2 Group E Member 3 (NR2E3) Antibody is a Rabbit Polyclonal antibody against Nuclear Receptor Subfamily 2 Group E Member 3 (NR2E3).

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Photoreceptor Cell Specific Nuclear Receptor / PNR (NR2E3)
Immunogen: Synthesized peptide derived from part region of human protein
Host
Rabbit
Reactivity
Human, Mouse
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by affinity chromatography using epitope-specific immunogen.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9Y5X4
Gene ID
10002
Alias
PNR,RNR,rd7,ESCS,RP37,Retina-specific nuclear receptor,Photoreceptor-specific nuclear receptor
Background
Antibody anti-NR2E3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Nuclear receptor subfamily 2 group E member 3 (NR2E3), also known as photoreceptor-specific nuclear receptor, is a nuclear receptor involved in the regulation of retinal development and the function of photoreceptors in the eye NR2E3 is specifically expressed in the retina, where it regulates the differentiation of photoreceptor cells, including rods and cones It plays a critical role in the development of the retina by influencing the expression of genes involved in the differentiation and maintenance of photoreceptors, which are essential for vision NR2E3 also controls the transcriptional network that governs the survival of retinal cells and the response to light Inherited mutations in NR2E3 are associated with retinal degenerative diseases, such as retinitis pigmentosa, which leads to progressive vision loss by impairing photoreceptor function In addition, NR2E3’s role in regulating the development of other retinal cell types and maintaining visual function makes it an important factor in ocular health and a potential target for therapeutic interventions in retinal diseases

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