Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody

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195€ (20 µl)

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935106861
info@markelab.com
name
Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001794
tested applications
ELISA, WB, IF/ICC

Description

PLCG2 Antibody is a Rabbit Polyclonal antibody against PLCG2. The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IF/ICC
Buffer
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P16885
Gene ID
5336
NCBI Accession
NP_002652.2
Background
Antibody anti-PLCG2
Status
RUO
Note
Concentration: > 0.2 mg/ml -

Descripción

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abx001794

Phospholipase C Gamma 2, Phosphatidylinositol Specific (PLCG2) Antibody

PLCG2 Antibody is a Rabbit Polyclonal antibody against PLCG2. The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Ver Producto