Phospho-EIF2S1 (Ser51) antibody antibody
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935106861
info@markelab.com
name
Phospho-EIF2S1 (Ser51) antibody antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10672
tested applications
ELISA, WB
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa (Phospho-EIF2S1 (Ser51)) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:1000-1:10000 |
| Clonality | monoclonal |
| Isotype | IgG1 |
| Clone ID | 9I7 |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P05198 |
| Alias | Eukaryotic translation initiation factor 2 subunit 1,Eukaryotic translation initiation factor 2 subunit alpha (eIF-2-alpha, eIF-2A, eIF-2alpha, eIF2-alpha),EIF2S1,EIF2A |
| Background | Antibody anti-EIF2S1 |
| Status | RUO |
| Note | Mol. Weight 36 kDa |
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EIF2S1 antibody
Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
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