PHD Finger Protein 11 Protein
234€ (5 µg)
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935106861
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name
PHD Finger Protein 11 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx260969
tested applications
SDS-PAGE
Description
PHF11 is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | PHF11 |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | Q9UIL8 |
| Alias | PHF11,BCAP,NY-REN-34,IGER,BRCA1 C-Terminus-Associated Protein,Renal Carcinoma Antigen NY-REN-34,NYREN34,IGHER,IGEL,APY |
| Background | Protein PHF11 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
PHF11 is a PHD domain-containing protein involved in transcriptional regulation and immune responses. It interacts with transcription factors and chromatin modifiers to regulate the expression of genes associated with inflammation, immune cell activation, and DNA repair. PHF11 plays a key role in enhancing transcriptional activity at specific genomic loci, particularly in B cells and T cells, where it regulates immune responses, including cytokine production and class-switch recombination. It is highly expressed in lymphoid tissues, supporting its role in adaptive immunity and lymphocyte function. Dysregulation of PHF11 is associated with autoimmune diseases, inflammatory disorders, and cancer, where altered transcriptional regulation disrupts immune balance and cell proliferation. Knockout studies demonstrate impaired immune responses, reduced antibody production, and defective lymphocyte activation, highlighting its importance in transcriptional regulation, immune system maintenance, and adaptive immunity.
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