Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A (FKBP12) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A (FKBP12) Immunogen: KLH-conjugated synthetic peptide between 43-74 amino acids from the Central region of human FKBP12. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 12 kDa |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P62942 |
| Background | Antibody anti-FKBP12 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A (FKBP12) Antibody
FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
Ver Producto
Human Peptidyl-Prolyl Cis-Trans Isomerase FKBP1A (FKBP12) Protein
Human FKBP12 Protein is a recombinant protein from Human produced in E. coli. A DNA sequence encoding the human FKBP12 (NP_463460) (Met 1-Glu 108) was expressed with a C-terminal polyhistidine tag.
Ver ProductoMouse Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1A (FKBP1A) Protein
Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1A (FKBP1A) protein is a recombinant Mouse protein expressed in E. coli.
Ver Producto