Peptidase Inhibitor 16 (PI16) Antibody
299€ (100 µl)
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935106861
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name
Peptidase Inhibitor 16 (PI16) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx102279
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Peptidase Inhibitor 16 (PI16).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Peptidase Inhibitor 16 (PI16) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6UXB8 |
| Gene ID | 221476 |
| Alias | CD364,PSPBP,CRISP9,MSMBBP,PI-16,Cysteine-rich secretory protein 9,PSP94-binding protein |
| Background | Antibody anti-PI16 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Peptidase Inhibitor 16 (PI16), also known as PSPBP (prostate secretory protein binding protein), is a member of the peptidase inhibitor family that plays a role in regulating protease activity in various tissues, particularly in the cardiovascular, immune, and reproductive systems. PI16 is a secreted protein expressed primarily by stromal fibroblasts, prostate cells, and cardiac tissues, among others. It has been identified as an immunomodulatory molecule and a marker for fibroblasts, especially those involved in tissue remodeling processes. By modulating protease activity, PI16 indirectly influences extracellular matrix (ECM) composition and cellular signaling, contributing to processes like fibrosis, inflammation, and cardiac function. Given its tissue-specific expression and involvement in immune responses, PI16 has been the subject of studies focused on its roles in cardiovascular diseases, cancer, and immune regulation.
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