Papilin (PAPLN) Antibody
383.5€ (100 µl)
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Name
Papilin (PAPLN) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx224019
Tested Applications
ELISA
Description
PAPLN Antibody is a Mouse Monoclonal against PAPLN.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Papilin (PAPLN) Immunogen: Purified recombinant fragment of human PAPLN (AA: 766-870) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Observed MW | 137.7 kDa |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95428 |
| Gene ID | 89932 |
| OMIM | 617785 |
| Alias | PPN |
| Background | Antibody anti-PAPLN |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Papilin, proteoglycan-like sulfated glycoprotein (PAPLN) is an extracellular matrix protein known for its multifaceted roles in tissue remodeling, development, and extracellular signaling. Its structure, rich in proteoglycan-like domains, allows it to interact with other matrix proteins, enzymes, and cell surface receptors, thereby influencing processes such as cell adhesion, migration, and differentiation. Papilin is highly expressed during embryogenesis, contributing to the formation and maintenance of tissues and organs. Aberrations in PAPLN expression or function have been associated with connective tissue abnormalities and may influence cancer cell invasion, highlighting its importance in both normal development and pathological conditions.
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