Pancreatic Alpha-Amylase (AMY2A) Antibody
292.5€ (80 µl)
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935106861
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name
Pancreatic Alpha-Amylase (AMY2A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx032511
tested applications
ELISA, WB, IF/ICC
Description
Amylases are secreted proteins that hydrolyze 1, 4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Pancreatic Alpha-Amylase (AMY2A) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04746 |
| Alias | AMY2 |
| Background | Antibody anti-AMY2A |
| Status | RUO |
Descripción
AMY2A, also known as pancreatic alpha-amylase, is an enzyme produced primarily in the pancreas, where it is secreted into the small intestine to continue the digestion of starch and glycogen. AMY2A hydrolyzes polysaccharides into maltose, maltotriose, and other smaller oligosaccharides, providing energy substrates for absorption and metabolism. It is a key enzyme in postprandial glucose regulation, supporting efficient carbohydrate digestion and nutrient absorption. AMY2A levels are commonly measured in clinical diagnostics as a marker of pancreatic function, particularly in conditions such as acute pancreatitis, pancreatic duct obstruction, and pancreatic cancer. Elevated AMY2A levels in serum or urine are indicative of pancreatic damage or inflammation. Variants in the AMY2A gene and abnormal amylase activity have also been linked to metabolic disorders such as obesity and diabetes, where altered carbohydrate digestion contributes to hyperglycemia and energy imbalance.
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