Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody
195€ (20 µl)
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935106861
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name
Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002213
tested applications
ELISA, WB
Description
PDX1 Antibody is a Rabbit Polyclonal antibody against PDX1. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Pancreas/duodenum Homeobox Protein 1 (PDX1) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P52945 |
| Gene ID | 3651 |
| Background | Antibody anti-PDX1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Pancreas/duodenum Homeobox Protein 1 (PDX1) Antibody
PDX1 Antibody is a Rabbit Polyclonal antibody against PDX1. The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
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