Palladin-Specific Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Palladin-Specific Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx236127
tested applications
ELISA, WB, IP
Description
Palladin-Specific Antibody is a Rabbit Polyclonal against Palladin-Specific.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Palladin-Specific |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/1000, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WX93 |
| Gene ID | 23022 |
| OMIM | 606856 |
| Alias | MYN,PNCA1,CGI151,SIH002,CGI-151,SIH002,Sarcoma antigen NY-SAR-83 |
| Background | Antibody anti-PALLD |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Palladin, cytoskeletal associated protein (PALLD) is a pivotal component of the cytoskeleton, playing a vital role in the organization, dynamics, and stability of actin filament networks within the cell. It acts as a scaffolding protein that binds directly to actin and other actin-associated proteins, thus facilitating the formation of stress fibers, lamellipodia, and other cellular structures critical for migration and adhesion. Palladin is especially active during developmental processes, tissue repair, and cancer metastasis, where enhanced cellular motility and structural remodeling are required. Mutations or dysregulation of PALLD have been linked to diseases such as cancer progression and certain connective tissue disorders, making it a key focus of cellular and molecular biology research.
