Palladin (PALLD) Antibody
312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Palladin (PALLD) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx126318
tested applications
WB, IHC, IF/ICC, IP
Description
PALLD Antibody is a Rabbit Polyclonal against PALLD.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Palladin (PALLD) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IP 50 - 1/200, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC, IP |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WX93 |
| Gene ID | 23022 |
| NCBI Accession | NP_001159582.1 |
| Alias | MYN,PNCA1,CGI151,SIH002,CGI-151,SIH002,Sarcoma antigen NY-SAR-77 |
| Background | Antibody anti-PALLD |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Palladin, cytoskeletal associated protein (PALLD) is a pivotal component of the cytoskeleton, playing a vital role in the organization, dynamics, and stability of actin filament networks within the cell. It acts as a scaffolding protein that binds directly to actin and other actin-associated proteins, thus facilitating the formation of stress fibers, lamellipodia, and other cellular structures critical for migration and adhesion. Palladin is especially active during developmental processes, tissue repair, and cancer metastasis, where enhanced cellular motility and structural remodeling are required. Mutations or dysregulation of PALLD have been linked to diseases such as cancer progression and certain connective tissue disorders, making it a key focus of cellular and molecular biology research.
