P21 (RAC1) Activated Kinase 3 (PAK3) Antibody
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935106861
info@markelab.com
Precio
292.5€ (80 µl)
Antibody anti-PAK3, RAC1
proveedor
Abbexareference
abx033768Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
PAK3, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. It shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein NCK. This protein is highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. PAK3 is autophosphorylated when activated by CDC42/p21. Defects in PAK3 are the cause of non-specific X-linked nonsyndromic mental retardation type 30 (MRX30). The protein structure contains 1 CRIB domain.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
P21 (RAC1) Activated Kinase 3 (PAK3)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purification
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
recommended dilution
WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
PAK3, RAC1
dry ice
No
availability
Shipped within 5-10 working days.
uniprot id
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P21 (RAC1) Activated Kinase 3 (PAK3) Antibody
proveedor
Abbexareference
abx033768Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalPAK3, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly w...
292.5€ (80 µl)
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