OX-2 Membrane Glycoprotein (CD200) Antibody (PE)
429€ (100 tests)
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935106861
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name
OX-2 Membrane Glycoprotein (CD200) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx139759
tested applications
FCM
Description
CD200 Antibody is a Mouse Monoclonal against CD200.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | OX-2 Membrane Glycoprotein (CD200) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 10 µl/100 µl of whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG1 Kappa |
| Clone ID | Q860 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P41217 |
| Gene ID | 4345 |
| Alias | OX-2 membrane glycoprotein,MRC,MOX1,MOX2,OX-2,My033 |
| Background | Antibody anti-CD200 |
| Status | RUO |
Descripción
CD200, also known as OX-2, is a membrane glycoprotein primarily involved in immune modulation. It is a member of the immunoglobulin superfamily and is widely expressed on various cell types, including neurons, epithelial cells, endothelial cells, thymocytes, and certain immune cells like B cells, T cells, and dendritic cells. CD200 plays a critical role in maintaining immune homeostasis by binding to its receptor, CD200R, predominantly on myeloid cells and some T cells. This interaction triggers an inhibitory signaling pathway that dampens immune responses, helping to prevent overactivation of the immune system and the development of autoimmunity. CD200 is implicated in a range of physiological and pathological processes, including immune tolerance, regulation of inflammation, tumor immunity, and protection of tissues from immune-mediated damage.
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