OX-2 Membrane Glycoprotein (CD200) Antibody

Este producto es parte de CD200 - CD200 molecule
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195€ (20 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
OX-2 Membrane Glycoprotein (CD200) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx006358
tested applications
ELISA, WB

Description

CD200 Antibody is a Rabbit Polyclonal Antibody against CD200.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
OX-2 Membrane Glycoprotein (CD200)
Host
Rabbit
Reactivity
Mouse, Rat
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P41217
Gene ID
4345
NCBI Accession
NP_005935.4
Alias
OX-2 membrane glycoprotein,MRC,MOX1,MOX2,OX-2,My033
Background
Antibody anti-CD200
Status
RUO
Note
Concentration: > 0.2 mg/ml - 

Descripción

CD200, also known as OX-2, is a membrane glycoprotein primarily involved in immune modulation. It is a member of the immunoglobulin superfamily and is widely expressed on various cell types, including neurons, epithelial cells, endothelial cells, thymocytes, and certain immune cells like B cells, T cells, and dendritic cells. CD200 plays a critical role in maintaining immune homeostasis by binding to its receptor, CD200R, predominantly on myeloid cells and some T cells. This interaction triggers an inhibitory signaling pathway that dampens immune responses, helping to prevent overactivation of the immune system and the development of autoimmunity. CD200 is implicated in a range of physiological and pathological processes, including immune tolerance, regulation of inflammation, tumor immunity, and protection of tissues from immune-mediated damage.

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