OX-2 Membrane Glycoprotein (CD200) Antibody

Este producto es parte de CD200 - CD200 molecule
Product Graph
741€ (1 ml)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
OX-2 Membrane Glycoprotein (CD200) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx171783
tested applications
WB, IHC, IF/ICC

Description

This product is currently in development. The lead time for this product may be several months. Please contact us at

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetOX-2 Membrane Glycoprotein (CD200)
HostMouse
ReactivityHuman
Recommended DilutionWB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConjugationUnconjugated
PurificationPurified by Protein A and Protein G affinity chromatography.
Size 11 ml
FormLiquid
Tested ApplicationsWB, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
AvailabilityPlease enquire.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
AliasOX-2 membrane glycoprotein,MRC,MOX1,MOX2,OX-2,My033
BackgroundAntibody anti-CD200
StatusRUO

Descripción

CD200, also known as OX-2, is a membrane glycoprotein primarily involved in immune modulation. It is a member of the immunoglobulin superfamily and is widely expressed on various cell types, including neurons, epithelial cells, endothelial cells, thymocytes, and certain immune cells like B cells, T cells, and dendritic cells. CD200 plays a critical role in maintaining immune homeostasis by binding to its receptor, CD200R, predominantly on myeloid cells and some T cells. This interaction triggers an inhibitory signaling pathway that dampens immune responses, helping to prevent overactivation of the immune system and the development of autoimmunity. CD200 is implicated in a range of physiological and pathological processes, including immune tolerance, regulation of inflammation, tumor immunity, and protection of tissues from immune-mediated damage.

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