OX-2 Membrane Glycoprotein (CD200) Antibody

Este producto es parte de CD200 - CD200 molecule
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182€ (25 µg)

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935106861
info@markelab.com
name
OX-2 Membrane Glycoprotein (CD200) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx413569
tested applications
IHC, FCM

Description

OX-2 Membrane Glycoprotein (CD200) Antibody is a Mouse Monoclonal antibody against OX-2 Membrane Glycoprotein (CD200).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetOX-2 Membrane Glycoprotein (CD200)
HostMouse
ReactivityHuman
Recommended DilutionValidated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConjugationUnconjugated
IsotypeIgG1
PurificationPurified
Size 125 µg
Size 2100 µg
Size 3200 µg
FormLiquid
Tested ApplicationsIHC, FCM
BufferPBS. Contains sodium azide.
AvailabilityShipped within 3-7 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP41217
AliasOX-2 membrane glycoprotein,MRC,MOX1,MOX2,OX-2,My033
BackgroundAntibody anti-CD200
StatusRUO
NoteConcentration: 1.0 mg/ml -

Descripción

CD200, also known as OX-2, is a membrane glycoprotein primarily involved in immune modulation. It is a member of the immunoglobulin superfamily and is widely expressed on various cell types, including neurons, epithelial cells, endothelial cells, thymocytes, and certain immune cells like B cells, T cells, and dendritic cells. CD200 plays a critical role in maintaining immune homeostasis by binding to its receptor, CD200R, predominantly on myeloid cells and some T cells. This interaction triggers an inhibitory signaling pathway that dampens immune responses, helping to prevent overactivation of the immune system and the development of autoimmunity. CD200 is implicated in a range of physiological and pathological processes, including immune tolerance, regulation of inflammation, tumor immunity, and protection of tissues from immune-mediated damage.
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