Osteomodulin (OMD) Antibody (FITC)

Este producto es parte de OMD - Osteomodulin
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169€ (20 µg)

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935106861
info@markelab.com
name
Osteomodulin (OMD) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx343994

Description

Osteomodulin (OMD) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human OMD.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Osteomodulin (OMD)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G chromatography.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q99983
Gene ID
4958
Alias
OSAD,SLRR2C,KSPG osteomodulin,Osteoadherin
Background
Antibody anti-OMD
Status
RUO

Descripción

Osteomodulin (OMD) is a small leucine-rich proteoglycan primarily expressed in the bone and cartilage, where it plays a key role in regulating extracellular matrix (ECM) structure and function OMD is involved in bone mineralization, collagen fibril organization, and cartilage development by interacting with collagen and other ECM components It contributes to skeletal integrity and has a significant impact on the mechanical properties of bone, influencing bone strength and elasticity OMD’s expression is upregulated during bone remodeling, and its role in cartilage integrity makes it crucial for joint health and skeletal repair Dysregulation of OMD expression has been associated with bone diseases such as osteogenesis imperfecta and osteoarthritis, where altered ECM composition leads to skeletal deformities and joint degradation Studies also suggest that OMD influences cell signaling pathways, particularly those related to osteoblast differentiation and function, highlighting its broader role in skeletal development and disease

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