Osteomodulin (OMD) Antibody
292.5€ (80 µl)
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935106861
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name
Osteomodulin (OMD) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx033423
tested applications
ELISA, WB, IHC
Description
OMD may be implicated in biomineralization processes. This protein has a function in binding of osteoblasts via the alpha (V) beta (3) integrin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Osteomodulin (OMD) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q99983 |
| Alias | OSAD,SLRR2C,KSPG osteomodulin,Osteoadherin |
| Background | Antibody anti-OMD |
| Status | RUO |
Descripción
Osteomodulin (OMD) is a small leucine-rich proteoglycan primarily expressed in the bone and cartilage, where it plays a key role in regulating extracellular matrix (ECM) structure and function OMD is involved in bone mineralization, collagen fibril organization, and cartilage development by interacting with collagen and other ECM components It contributes to skeletal integrity and has a significant impact on the mechanical properties of bone, influencing bone strength and elasticity OMD’s expression is upregulated during bone remodeling, and its role in cartilage integrity makes it crucial for joint health and skeletal repair Dysregulation of OMD expression has been associated with bone diseases such as osteogenesis imperfecta and osteoarthritis, where altered ECM composition leads to skeletal deformities and joint degradation Studies also suggest that OMD influences cell signaling pathways, particularly those related to osteoblast differentiation and function, highlighting its broader role in skeletal development and disease
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