Opsin 3 (OPN3) Antibody
221€ (50 µg)
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935106861
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name
Opsin 3 (OPN3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx326228
tested applications
ELISA, WB, IHC, IF/ICC
Description
OPN3 Antibody is a Rabbit Polyclonal against OPN3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Opsin 3 (OPN3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/5000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H1Y3 |
| Gene ID | 23596 |
| Alias | OPN3,ECPN,Encephalopsin,Panopsin,opsin 3,PPP1R116 |
| Background | Antibody anti-OPN3 |
| Status | RUO |
Descripción
Opsin-3 (OPN3), also known as panopsin, is a type of opsin found in various tissues, including the retina and brain, where it plays a role in non-visual light perception. Unlike the opsins involved in color vision (such as those in cone cells), opsin-3 is involved in regulating responses to light in non-visual pathways, including circadian rhythm regulation and the modulation of other physiological processes. It is particularly important for the detection of light in the blue spectrum and is expressed in retinal ganglion cells, which are involved in setting the body's internal clock. OPN3 contributes to the synchronization of the circadian rhythm, which governs sleep-wake cycles and other physiological processes tied to the day-night cycle. The role of OPN3 in the brain suggests that it may influence mood, behavior, and other cognitive functions. Disruptions in the function of opsin-3 have been implicated in disorders such as seasonal affective disorder (SAD) and sleep disorders. Understanding OPN3 can provide insights into circadian rhythm regulation and the effects of light exposure on human health.
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