Opioid Receptor Delta 1 (OPRD1) Antibody
273€ (200 µl)
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935106861
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name
Opioid Receptor Delta 1 (OPRD1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx433072
tested applications
P-ELISA
Description
OPRD1 Antibody is a Goat Polyclonal antibody against OPRD1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Opioid Receptor Delta 1 (OPRD1) |
| Host | Goat |
| Recommended Dilution | P-ELISA: 1/8000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 4985 |
| NCBI Accession | NP_000902.3 |
| Alias | OPRD1,DOP,DOR,OP1,Delta receptor,DOR-1,DOPr,opioid receptor,OPRD |
| Background | Antibody anti-OPRD1 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
OPRD1, also known as the delta-opioid receptor, is a G protein-coupled receptor (GPCR) activated by endogenous opioid peptides such as enkephalins. It is expressed in the central nervous system (CNS), including the cortex, limbic system, and spinal cord, where it modulates pain perception, mood regulation, and neuroprotection. OPRD1 couples to Gi/o proteins, inhibiting adenylate cyclase activity, reducing cAMP levels, and modulating ion channel activity to decrease neuronal excitability. Activation of OPRD1 produces analgesic effects, particularly in chronic and neuropathic pain conditions. It is also involved in regulating mood and emotional behaviors, with potential roles in reducing anxiety and depressive symptoms. Dysregulation of OPRD1 has been linked to pain disorders, addiction, and mood dysregulation. Selective OPRD1 agonists are being explored for their analgesic properties with lower addiction potential compared to mu-opioid receptor agonists. OPRD1 modulation represents a promising therapeutic approach for pain management, mood disorders, and neuroprotection.
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