Opioid Receptor Cell ELISA Kit
513.5€ (96 tests)
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935106861
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name
Opioid Receptor Cell ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx595434
tested applications
ELISA
Description
Opioid Receptor Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Opioid Receptor |
| Reactivity | Human, Mouse, Rat |
| Detection Method | Colorimetric |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Tested Applications | ELISA |
| Availability | Shipped within 1-2 weeks. The validity for this kit is at least 6 months |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P35372 |
| Gene ID | 4988 |
| OMIM | 600018 |
| Alias | OPRD1,DOP,DOR,OP1,Delta receptor,DOR-1,DOPr,opioid receptor,OPRD |
| Background | Elisa kits for OPRD1 |
| Status | RUO |
| Note | Validity: 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
OPRD1, also known as the delta-opioid receptor, is a G protein-coupled receptor (GPCR) activated by endogenous opioid peptides such as enkephalins. It is expressed in the central nervous system (CNS), including the cortex, limbic system, and spinal cord, where it modulates pain perception, mood regulation, and neuroprotection. OPRD1 couples to Gi/o proteins, inhibiting adenylate cyclase activity, reducing cAMP levels, and modulating ion channel activity to decrease neuronal excitability. Activation of OPRD1 produces analgesic effects, particularly in chronic and neuropathic pain conditions. It is also involved in regulating mood and emotional behaviors, with potential roles in reducing anxiety and depressive symptoms. Dysregulation of OPRD1 has been linked to pain disorders, addiction, and mood dysregulation. Selective OPRD1 agonists are being explored for their analgesic properties with lower addiction potential compared to mu-opioid receptor agonists. OPRD1 modulation represents a promising therapeutic approach for pain management, mood disorders, and neuroprotection.
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