O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody

383.5€ (100 µl)
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935106861
info@markelab.com
name
O-6-Methylguanine DNA Methyltransferase (MGMT) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx224153
tested applications
ELISA
Description
MGMT Antibody is a Mouse Monoclonal against MGMT.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | O-6-Methylguanine DNA Methyltransferase (MGMT) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Isotype | IgG1 |
Purification | Purified from ascites by Protein G chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA |
Buffer | PBS, containing 0.05% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P16455 |
Gene ID | 4255 |
OMIM | 156569 |
Background | Antibody anti-MGMT |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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