MGMT antibody
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935106861
info@markelab.com
name
MGMT antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05169
tested applications
ELISA, WB, IHC
Description
Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | O-6-methylguanine-DNA methyltransferase (MGMT) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 22 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P16455 |
| Gene ID | 4255 |
| Alias | Methylated-DNA--protein-cysteine methyltransferase,6-O-methylguanine-DNA methyltransferase (MGMT),O-6-methylguanine-DNA-alkyltransferase,MGMT |
| Background | Antibody anti-MGMT |
| Status | RUO |
| Note | Mol. Weight 22 kDa |
Descripción
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Human MGMT (Methylated-DNA--protein-cysteine methyltransferase) ELISA Kit
Ver Producto
MGMT antibody
Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Ver ProductoMGMT antibody
Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Ver Producto