Nucleus Accumbens-Associated Protein 2 (NACC2) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleus Accumbens-Associated Protein 2 (NACC2) Immunogen: KLH-conjugated synthetic peptide between 473-502 amino acids from the C-terminal region of human NACC2. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 62.8 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96BF6 |
| Background | Antibody anti-NACC2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
Nucleus Accumbens-Associated Protein 2 (NACC2) Antibody
BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.
Ver Producto
Human Nucleus accumbens-associated protein 2 (NACC2) ELISA Kit
Human Nucleus accumbens-associated protein 2 (NACC2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NACC2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto
Mouse Nucleus accumbens-associated protein 2 (NACC2) ELISA Kit
Mouse Nucleus accumbens-associated protein 2 (NACC2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse NACC2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto