Nucleosome Assembly Protein 1 Like Protein 1 (NAP1L1) Antibody
195€ (20 µl)
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935106861
info@markelab.com
name
Nucleosome Assembly Protein 1 Like Protein 1 (NAP1L1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002085
tested applications
ELISA, WB
Description
NAP1L1 Antibody is a Rabbit Polyclonal antibody against NAP1L1. This gene encodes a member of the nucleosome assembly protein (NAP) family. This protein participates in DNA replication and may play a role in modulating chromatin formation and contribute to the regulation of cell proliferation. Alternative splicing of this gene results in several transcript variants; however, not all have been fully described.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleosome Assembly Protein 1 Like Protein 1 (NAP1L1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P55209 |
| Gene ID | 4673 |
| Alias | NRP,NAP1,NAP1L,NAP-1-related protein,Hnrp |
| Background | Antibody anti-NAP1L1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
Nucleosome assembly protein 1 like 1 (NAP1L1) is a protein involved in chromatin remodeling and nucleosome assembly, playing an essential role in regulating gene expression and DNA repair NAP1L1 functions by facilitating the assembly of nucleosomes, which are the structural units of chromatin, ensuring that DNA is packaged efficiently into the nucleus while remaining accessible for transcription and replication The protein interacts with histones and other chromatin components to assemble and disassemble nucleosomes, enabling the dynamic regulation of gene expression in response to cellular needs NAP1L1 is involved in maintaining genomic stability, as proper nucleosome assembly is crucial for DNA repair and the prevention of DNA damage Dysregulation of NAP1L1 expression or function can lead to various diseases, including cancers and developmental disorders, where faulty chromatin assembly and gene regulation contribute to tumor progression or developmental abnormalities In addition, NAP1L1 is implicated in the regulation of cell cycle progression, influencing cell division and differentiation processes Its role in chromatin dynamics, gene regulation, and DNA repair underscores its importance in maintaining normal cellular function and preventing disease
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