anti- NAP1L1 antibody
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935106861
info@markelab.com
name
anti- NAP1L1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05544
tested applications
ELISA, WB, IHC, IF, FC, IP
Description
May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | nucleosome assembly protein 1-like 1 |
| Host | Rabbit |
| Reactivity | human,mouse,rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 55-60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, FC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P55209 |
| Gene ID | 4673 |
| Alias | NRP,NAP1,NAP1L,NAP-1-related protein,Hnrp |
| Background | Antibody anti-NAP1L1 |
| Status | RUO |
| Note | This product is for research use only. |
Descripción
Nucleosome assembly protein 1 like 1 (NAP1L1) is a protein involved in chromatin remodeling and nucleosome assembly, playing an essential role in regulating gene expression and DNA repair NAP1L1 functions by facilitating the assembly of nucleosomes, which are the structural units of chromatin, ensuring that DNA is packaged efficiently into the nucleus while remaining accessible for transcription and replication The protein interacts with histones and other chromatin components to assemble and disassemble nucleosomes, enabling the dynamic regulation of gene expression in response to cellular needs NAP1L1 is involved in maintaining genomic stability, as proper nucleosome assembly is crucial for DNA repair and the prevention of DNA damage Dysregulation of NAP1L1 expression or function can lead to various diseases, including cancers and developmental disorders, where faulty chromatin assembly and gene regulation contribute to tumor progression or developmental abnormalities In addition, NAP1L1 is implicated in the regulation of cell cycle progression, influencing cell division and differentiation processes Its role in chromatin dynamics, gene regulation, and DNA repair underscores its importance in maintaining normal cellular function and preventing disease
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