NAP1L1 antibody

Este producto es parte de NAP1L - nucleosome assembly protein 1 like
NAP1L1 antibody
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Name
NAP1L1 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab05544
Tested Applications
ELISA, WB, IHC, IF, FC, IP

Description

May be involved in modulating chromatin formation and contribute to regulation of cell proliferation.

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
nucleosome assembly protein 1-like 1 (NAP1L1)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
55-60 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF, FC, IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P55209
Gene ID
4673
Alias
NRP,NAP1,NAP1L,NAP-1-related protein,Hnrp
Background
Antibody anti-NAP1L1
Status
RUO
Note
Mol. Weight 55-60 kDa

Background

Nucleosome assembly protein 1 like 1 (NAP1L1) is a protein involved in chromatin remodeling and nucleosome assembly, playing an essential role in regulating gene expression and DNA repair NAP1L1 functions by facilitating the assembly of nucleosomes, which are the structural units of chromatin, ensuring that DNA is packaged efficiently into the nucleus while remaining accessible for transcription and replication The protein interacts with histones and other chromatin components to assemble and disassemble nucleosomes, enabling the dynamic regulation of gene expression in response to cellular needs NAP1L1 is involved in maintaining genomic stability, as proper nucleosome assembly is crucial for DNA repair and the prevention of DNA damage Dysregulation of NAP1L1 expression or function can lead to various diseases, including cancers and developmental disorders, where faulty chromatin assembly and gene regulation contribute to tumor progression or developmental abnormalities In addition, NAP1L1 is implicated in the regulation of cell cycle progression, influencing cell division and differentiation processes Its role in chromatin dynamics, gene regulation, and DNA repair underscores its importance in maintaining normal cellular function and preventing disease

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