Nucleosome Assembly Protein 1-Like 2 (NAP1L2) Antibody
312€ (60 µl)
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Name
Nucleosome Assembly Protein 1-Like 2 (NAP1L2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx126218
Tested Applications
WB
Description
NAP1L2 Antibody is a Rabbit Polyclonal against NAP1L2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Nucleosome Assembly Protein 1-Like 2 (NAP1L2) Immunogen: Recombinant fusion protein corresponding to human NAP1L2 |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 37 kDa/52 kDa Observed MW: 55 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULW6 |
| Gene ID | 4674 |
| NCBI Accession | NP_068798.1 |
| Alias | BPX,Brain-specific protein, X-linked |
| Background | Antibody anti-NAP1L2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Nucleosome assembly protein 1 like 2 (NAP1L2) is a chromatin-remodeling protein that plays a crucial role in the assembly and disassembly of nucleosomes, the basic structural units of chromatin NAP1L2 is involved in the regulation of gene expression by facilitating the proper packaging of DNA into nucleosomes while allowing access to the genetic material for transcription, replication, and repair The protein aids in the dynamic regulation of chromatin structure, influencing DNA accessibility and the function of transcription factors, histone-modifying enzymes, and other chromatin-associated proteins NAP1L2’s role in maintaining chromatin homeostasis is essential for normal cell function, particularly during cell cycle progression, DNA repair, and cellular differentiation Dysregulation of NAP1L2 expression or function is associated with genomic instability and cancer, where abnormal chromatin assembly can lead to defective gene expression and uncontrolled cell proliferation NAP1L2’s involvement in DNA damage response pathways underscores its importance in maintaining cellular integrity and preventing diseases such as cancer and developmental disorders
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