Nucleoporin NUP42 / NUPL2 (NUP42) Antibody (HRP)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Nucleoporin NUP42 / NUPL2 (NUP42) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx304685
tested applications
ELISA
Description
NUP42 Antibody (HRP) is a Rabbit Polyclonal against NUP42 conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin NUP42 / NUPL2 (NUP42) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O15504 |
| Gene ID | 11097 |
| NCBI Accession | NP_031368.1, NM_007342.2 |
| Alias | CG1,NLP1,UIP1,Hcg1,NLP-1,NLP_1,NUPL2,Nucleoporin-like protein 2, nucleoporin-like protein 1 |
| Background | Antibody anti-NUP42 |
| Status | RUO |
Descripción
Nucleoporin 42 (NUP42), also known as NupL1, is a component of the nuclear pore complex (NPC), which regulates the bidirectional transport of macromolecules such as RNA and proteins between the nucleus and cytoplasm. NUP42 is specifically associated with the cytoplasmic face of the NPC and plays a critical role in mRNA export and other transport pathways. It interacts with the CRM1 export receptor, facilitating the export of certain cargoes during cellular stress responses and viral infections. Mutations or dysregulation of NUP42 can affect nucleocytoplasmic transport, contributing to cellular senescence, developmental defects, and diseases such as cancer and neurodegenerative disorders. Understanding its function provides insights into the dynamics of nuclear-cytoplasmic communication and the mechanisms underlying related pathologies.
Related Products
NUP42 antibody
Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope.
Ver Producto
Nucleoporin NUP42 / NUPL2 (NUP42) Antibody
Required for the export of mRNAs containing poly (A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope.
Ver Producto
Nucleoporin Like 2 (NUP42) Antibody
Nucleoporin Like 2 Antibody is a Rabbit Polyclonal antibody against Nucleoporin Like 2.
Ver Producto