Nucleoporin GLE1 (GLE1) Antibody (Biotin)

Este producto es parte de GLE1 - RNA export mediator
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169€ (20 µg)

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935106861
info@markelab.com
name
Nucleoporin GLE1 (GLE1) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx307433
tested applications
ELISA

Description

GLE1 Antibody (Biotin) is a Rabbit Polyclonal against GLE1 conjugated to Biotin.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Nucleoporin GLE1 (GLE1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Biotin
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q53GS7
Gene ID
2733
NCBI Accession
NP_001003722.1, NM_001003722.1
OMIM
253310
Alias
LCCS,CAAHC,CAAHD,GLE1L,LCCS1,Hgle1,GLE1 RNA export mediator,GLE1-like protein,Nucleoporin GLE1
Background
Antibody anti-GLE1
Status
RUO

Descripción

GLE1 RNA export mediator is a key protein involved in the export of RNA from the nucleus to the cytoplasm, a critical step in gene expression regulation GLE1 interacts with the RNA exosome complex and other nuclear export factors to facilitate the release of mature RNA molecules from the nuclear pore complex It plays a significant role in the transport of messenger RNAs (mRNAs) and other RNA species, such as ribosomal RNA (rRNA) and transfer RNA (tRNA), ensuring that they are correctly processed and transported for translation in the cytoplasm GLE1’s involvement in RNA export is essential for maintaining cellular homeostasis, and defects in this process are linked to several neurological disorders and cancers Additionally, GLE1 has been shown to participate in the regulation of nuclear envelope dynamics, highlighting its multifaceted role in cellular function and RNA metabolism

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