Nucleoporin GLE1 (GLE1) Antibody (Biotin)

169€ (20 µg)
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935106861
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name
Nucleoporin GLE1 (GLE1) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx307433
tested applications
ELISA
Description
GLE1 Antibody (Biotin) is a Rabbit Polyclonal against GLE1 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Nucleoporin GLE1 (GLE1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Biotin |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q53GS7 |
Gene ID | 2733 |
NCBI Accession | NP_001003722.1, NM_001003722.1 |
OMIM | 253310 |
Alias | LCCS,CAAHC,CAAHD,GLE1L,LCCS1,Hgle1,GLE1 RNA export mediator,GLE1-like protein,Nucleoporin GLE1 |
Background | Antibody anti-GLE1 |
Status | RUO |
Descripción
GLE1 RNA export mediator is a key protein involved in the export of RNA from the nucleus to the cytoplasm, a critical step in gene expression regulation GLE1 interacts with the RNA exosome complex and other nuclear export factors to facilitate the release of mature RNA molecules from the nuclear pore complex It plays a significant role in the transport of messenger RNAs (mRNAs) and other RNA species, such as ribosomal RNA (rRNA) and transfer RNA (tRNA), ensuring that they are correctly processed and transported for translation in the cytoplasm GLE1’s involvement in RNA export is essential for maintaining cellular homeostasis, and defects in this process are linked to several neurological disorders and cancers Additionally, GLE1 has been shown to participate in the regulation of nuclear envelope dynamics, highlighting its multifaceted role in cellular function and RNA metabolism
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