Nucleoporin GLE1 (GLE1) Antibody

Background

GLE1 RNA export mediator is a key protein involved in the export of RNA from the nucleus to the cytoplasm, a critical step in gene expression regulation GLE1 interacts with the RNA exosome complex and other nuclear export factors to facilitate the release of mature RNA molecules from the nuclear pore complex It plays a significant role in the transport of messenger RNAs (mRNAs) and other RNA species, such as ribosomal RNA (rRNA) and transfer RNA (tRNA), ensuring that they are correctly processed and transported for translation in the cytoplasm GLE1’s involvement in RNA export is essential for maintaining cellular homeostasis, and defects in this process are linked to several neurological disorders and cancers Additionally, GLE1 has been shown to participate in the regulation of nuclear envelope dynamics, highlighting its multifaceted role in cellular function and RNA metabolism