Nucleoporin 37 kDa (NUP37) Antibody
273€ (100 µl)
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935106861
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name
Nucleoporin 37 kDa (NUP37) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx131416
tested applications
WB, IHC, IF/ICC
Description
Nucleoporin 37 kDa Antibody is a Rabbit Polyclonal against Nucleoporin 37 kDa.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nucleoporin 37 kDa (NUP37) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | p37,MCPH24,Nup107-160 subcomplex subunit Nup37 |
| Background | Antibody anti-NUP37 |
| Status | RUO |
Descripción
Nucleoporin 37 (NUP37) is another important nucleoporin that contributes to the structure and function of the nuclear pore complex NUP37 interacts with other nucleoporins to form the central channel of the nuclear pore, allowing for the selective exchange of macromolecules between the nucleus and cytoplasm It plays a role in RNA processing and transport, ensuring that RNA molecules are correctly exported from the nucleus to the cytoplasm for protein synthesis NUP37 is also involved in the regulation of cell cycle progression and transcriptional control, as its function in nuclear-cytoplasmic transport affects gene expression and cellular responses to external stimuli Defects in NUP37 have been associated with various disorders, including certain types of cancer and neurodevelopmental diseases, where impaired nuclear pore function disrupts cellular homeostasis and protein synthesis
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