Nuclear Valosin-Containing Protein-Like (NVL) Antibody
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Description
NVL Antibody is a Rabbit Polyclonal antibody against NVL. This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nuclear Valosin-Containing Protein-Like (NVL) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O15381 |
| Gene ID | 4931 |
| NCBI Accession | NP_001230076.1 |
| Background | Antibody anti-NVL |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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NVL antibody
Participates in the assembly of the telomerase holoenzyme and effecting of telomerase activity via its interaction with TERT(PubMed:22226966). May play a role in 60S ribosomal subunit biogenesis(PubMed:15469983, PubMed:16782053).
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Nuclear Valosin-Containing Protein-Like (NVL) Antibody
NVL Antibody is a Rabbit Polyclonal antibody against NVL. This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.
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Nuclear Valosin-Containing Protein-Like (NVL) Antibody
NVL Antibody is a Rabbit Polyclonal antibody against NVL.
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