Nuclear Receptor Subfamily 2 Group C Member 2 (NR2C2) Antibody
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Description
Nuclear Receptor Subfamily 2 Group C Member 2 (NR2C2) Antibody is a Rabbit polyclonal antibody for the detection of Human Nuclear Receptor Subfamily 2 Group C Member 2 (NR2C2).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nuclear Receptor Subfamily 2 Group C Member 2 (NR2C2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49116 |
| Gene ID | 7182 |
| NCBI Accession | NP_001278623.1 |
| Alias | TR4,TAK1,Testicular receptor 4,Orphan nuclear receptor TR4,Orphan nuclear receptor TAK1 |
| Background | Antibody anti-NR2C2 |
| Status | RUO |
Descripción
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Human NR2C2 (Nuclear receptor subfamily 2 group C member 2) ELISA Kit
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NR2C2 antibody
Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED(direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements(HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior(By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.
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