Nuclear Receptor Subfamily 2 Group C Member 2 (NR2C2) Antibody

Background

Nuclear receptor subfamily 2 group C member 2 (NR2C2), also known as TR4, is a nuclear receptor involved in regulating various biological processes, including development, metabolism, and cellular differentiation NR2C2 functions by binding to specific DNA sequences, known as hormone response elements (HREs), and modulating the transcription of genes involved in processes like cell cycle regulation, lipid metabolism, and gene expression NR2C2 is expressed in tissues such as the liver, heart, and brain, where it contributes to the regulation of metabolic processes and cellular growth During development, NR2C2 plays a role in the regulation of neuronal differentiation and the development of the central nervous system Dysregulation of NR2C2 has been linked to disorders such as cancer, where its altered expression may influence tumor growth and metastasis In addition, NR2C2 is involved in regulating the immune system, and its dysfunction can lead to conditions like autoimmune diseases and inflammatory disorders, highlighting its importance in maintaining cellular and systemic homeostasis