Nuclear Receptor Subfamily 2 Group C Member 1 (NR2C1) Antibody

Este producto es parte de NR2C - nuclear receptor subfamily 2 group C member
Nuclear Receptor Subfamily 2 Group C Member 1 (NR2C1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

169€ (20 µl)

Antibody anti-NR2C1

proveedor

Abbexa

reference

abx321546

Tested Applications

ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

NR2C1 Antibody is a Rabbit Polyclonal against NR2C1.


Background

Nuclear receptor subfamily 2 group C member 1 (NR2C1), also known as TR2, is a nuclear receptor that is involved in regulating various biological processes, including development, metabolism, and cellular differentiation NR2C1 is expressed in a variety of tissues, including the brain, liver, and reproductive organs, where it plays a role in regulating the expression of genes involved in lipid metabolism, steroidogenesis, and cellular growth It functions by binding to specific DNA sequences and modulating the transcription of target genes, influencing both developmental processes and the regulation of metabolic pathways NR2C1 also plays a role in the regulation of the immune system, where it helps control the expression of genes involved in immune responses and inflammation Dysregulation of NR2C1 has been associated with disorders such as cancer, where altered nuclear receptor activity can contribute to tumor progression and metastasis Additionally, NR2C1 is implicated in the regulation of circadian rhythms and reproductive health, highlighting its importance in maintaining cellular and systemic homeostasis Its involvement in development, metabolism, and immune function positions NR2C1 as a potential therapeutic target for diseases related to hormonal imbalances, inflammation, and cancer

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Nuclear Receptor Subfamily 2 Group C Member 1 (NR2C1)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC


purification

Antigen Affinity Chromatography.


recommended dilution

WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.


buffer

PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.


size 1

20 µl


size 2

50 µl


size 3

100 µl


size 4

200 µl


size 5

1 ml


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

NR2C1


dry ice

No


availability

Shipped within 5-10 working days.


alias

TR2,Orphan nuclear receptor TR2,Testicular receptor 2


NCBI accession

NP_001027458.1, NM_001032287.2, NP_001120834.1, NM_001127362.1, NP_003288.2, NM_003297.3


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