Name: anti- NR2C1 antibody
Brand: FineTest
SKU: FNab05840
Availability: OnlineOnly

Descripción

Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements(HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED(direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

nuclear receptor subfamily 2, group C, member 1

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC

observerd MW

52kd

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

NR2C1

alias

TR2,Orphan nuclear receptor TR2,Testicular receptor 2

uniprot id

https://www.uniprot.org/uniprotkb/P13056

gene id

https://www.ncbi.nlm.nih.gov/gene/7181

note

This product is for research use only.

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Human NR2C1(Nuclear receptor subfamily 2 group C member 1) ELISA Kit

proveedor

FineTest

reference

EH10642

reactivity

human

status

RUO

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